The RICU

An Attack on the Plaque

An Attack on the Plaque: Fighting Alzheimer’s Disease using a monoclonal antibody against Beta-Amyloid plaque build-up. 

A cure for Alzheimer’s Disease remains frustratingly elusive to scientists and clinicians. The characteristic build-up of beta-amyloid protein and hyper-phosphorylated Tau protein causes irreversible damage to cognitive function and memory. In this week’s episode, we’ll dive into a fascinating discussion on a breakthrough monoclonal antibody that reduces the build-up of plaque in the brain. It’s like fluoride for the brain! (Although not yet recommended by 9/10 neurologists). 

The implications of this journal article are astounding. We hope you enjoy this episode! 

Hold the Haldol: Exploring the Role of Cholinergics in Schizophrenia

Until now, schizophrenia and other psychotic diseases were consistently treated with heavy duty, anti-dopaminergic, anti-psychotic medications. These drugs- both first and second generation- carry serious and sometimes irreversible adverse effects (think: EPS, NMS, etc.)
In today’s episode, we’ll discuss a groundbreaking phase-2 clinical trial exploring the use of a muscarinic agonist in the treatment of schizophrenia. Worried about DUMBBELLS? So were we! But these researchers have designed a truly elegant cholinergic/anti-cholinergic duet.

This is an exciting article you don’t want to miss out on!

Keratinocytes Actin' Out: Treating AK in Record Breaking Time

Dermatological lesions can sometimes feel confusing to diagnose. Skin lesions can often be benign, but you never want to miss a precancerous one. In today’s discussion, we’ll help you nail down a diagnosis of actinic keratosis and what to prescribe based on the latest evidence-based research.

The Biggest Loser

A Follicular Rescue Mission

A Follicular Rescue Mission: Letrozole as first line treatment for infertility in PCOS.

The patient suffering from Polcystic Ovarian Syndrome isn’t hard to spot. Typically obese, male-pattern hair growth, irregular periods, unsuccessful attempts at fertility and the characteristic overgrowth of ovarian cysts on Ultrasound. We all know it. 

But how do we help our patients suffering from this painful disease? Can we actually resolve their infertility? Tune in to this weeks podcast as we discuss the somewhat confusing pathophysiology of PCOS and what the research has shown to be life changing treatment for these women. 

A (Very) Clean Break From Smoking

A (Very) Clean Break from Smoking: Utilizing a Pharmacolgic Approach”
We don’t need to be reminded of the myriad of detrimental effects tobacco smoking has on our patients health. Why don’t we have more powerful strategies to help our patients quit smoking?

Today’s article explores the pharmacological approach to smoking cessation and provides a definitive and perhaps game changing solution.

It’s up to us, as physicians and providers, to take a stronger stance against failed smoking cessation attempts. We hope that you will walk away with the information from this clinical research article with a more determined strategy to help your patients definitively quit smoking utilizing a combined behavioral and pharmacological approach.

Dual Antiplatelet Therapy?

What medication does one give after a patient has a stroke?