Hold the Haldol: Exploring the Role of Cholinergics in Schizophrenia

Until now, schizophrenia and other psychotic diseases were consistently treated with heavy duty, anti-dopaminergic, anti-psychotic medications. These drugs- both first and second generation- carry serious and sometimes irreversible adverse effects (think: EPS, NMS, etc.)
In today’s episode, we’ll discuss a groundbreaking phase-2 clinical trial exploring the use of a muscarinic agonist in the treatment of schizophrenia. Worried about DUMBBELLS? So were we! But these researchers have designed a truly elegant cholinergic/anti-cholinergic duet.

This is an exciting article you don’t want to miss out on!